A 77-year-old man phones ‘999’ after experiencing severe backache. The paramedics arrive to find him in severe pain, and cold and clammy. While at his house, they note that he smokes and also elicit a history of hypertension. He is tachycardic and hypotensive en route to hospital, and intravenous fluids are started. You have been assigned his initial assessment ...

100 Cases in Clinical Pathology and Laboratory Medicine presents 100 clinical scenarios commonly seen by medical students and junior doctors in the emergency department, outpatient clinic, operating theatre or in general practice. A succinct summary of the patient's history, examination and initial investigations is followed by questions on each case, with particular emphasis on the interpretation of the results and in which an understanding of the underlying clinical pathology is central to arriving at the correct diagnosis. The answer includes a detailed discussion on each topic, providing an essential revision aid as well as a practical guide for students and junior doctors, especially those preparing for undergraduate and postgraduate examinations.

Making speedy and appropriate clinical decisions, and choosing the best course of action to take as a result, is one of the most important and challenging parts of training to become a doctor. Fully revised and updated for this second edition, these true-to-life cases will teach students and junior doctors to recognize important clinical conditions, to request the appropriate pathological investigation and correctly interpret those results, and, as a result, to develop their diagnostic and management skills.

Eamon Shamil MBBS, MRes, DOHNS, FRCS (ORL-HNS) Post-CCT Fellow in Rhinology, Anterior Skull Base, and Facial Plastic Surgery, The Royal National ENT Hospital, University College London Hospitals NHS Foundation Trust, London, UK

Praful Ravi MA MB BChir MRCP Attending Physician in Genitourinary Oncology, Dana-Farber Cancer Institute; Instructor of Medicine, Harvard Medical School, Boston, USA

Ashish Chandra FRCPath DipRCPath (Cytol) Lead Consultant for Cytopathology & Urological Histopathology, Guy’s and St Thomas’ NHS Foundation Trust, London, UK; Chair, British Association of Urological Pathologists (BAUP); Vice President, International Academy of Cytology (IAC); Deputy Editor, Cytopathology