Ion Channels of Excitable Membranes

Ion Channels of Excitable Membranes

by Bertil Hille (Author)


This fully revised and expanded third edition of "Ionic Channels of Excitable Membranes" describes the known channels and their physiological functions, then develops the conceptual background needed to understand their architecture and molecular mechanisms of operation. It includes new chapters on calcium signalling, structural biology, and molecular biology and genomics. The text begins with the classical biophysical work of Hodgkin and Huxley, continues with the roles of channels in cellular signaling, then develops the physical and molecular principles needed for explaining permeation, gating, pharmacological modification, and molecular diversity, and ends with a discussion of channel evolution. It is written to be accessible and interesting to life scientists and physical scientists of all kinds. It introduces all the concepts that a graduate student should be aware of but is also effective in advanced undergraduate courses.


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More Information

Format: Hardcover
Pages: 814
Edition: 3rd edition
Publisher: Sinauer Associates Inc.,U.S.
Published: 30 Aug 2001

ISBN 10: 0878933212
ISBN 13: 9780878933211